NFL Betting Preview: San Francisco 49ers vs. Arizona Cardinals – Saturday, Dec. 26, 2020

The Arizona Cardinals will take on the San Francisco 49ers chasing a playoff spot in the NFC West division. The Cardinals have won their last two games and are coming into this game, just one game out of a playoff spot. The 49ers are in a much different position and are trying to find a way to get this season over with.

Kickoff for this game is scheduled for 3:30 central time at State Farm Stadium in Glendale Arizona. The last time these two teams met, September 13th, the Cardinals won the game 24-20. This game will look a little different due to the injuries the 49ers have been dealing with all season.

San Francisco 49ers Betting Preview: Trying to finish the season on a positive.

The 49ers come into this game with a 5-9 record. San Francisco started off the season 4-3 when their quarterback, Jimmy Garoppolo, went down with a severe ankle sprain. Since week 7 they are just 1-6 with Nick Mullens under center. Mullens has thrown 12 touchdowns as well as 12 interceptions. With Mullens under center, the 49ers are only averaging 21.7 points per game.

The bright spot for San Francisco has been rookie wide receiver Brandon Aiyuk. The first rounder from Arizona state has pulled in 59 receptions and has 7 total touchdowns.

The other offensive weapon would be the running back Raheem Mostert. Mostert has not been at his best this season but is still getting 5 yards per carry,

Arizona Cardinals Betting Preview: Fighting for the playoffs.

Arizona is coming into Saturday with an 8-6 record. They have won their last two games and are finding ways to get the job done. Quarterback Kyler Murray has been one of the main reasons for the Cardinals success.

Through 14 games, Murray has been able to find the end zone 26 times through the air and ran for touchdowns 11 times. He has only been responsible for 11 interceptions as well this season.

The Cardinals have a stellar wide receiving core. DeAndre Hopkins, Christian Kirk and Larry Fitzgerald each bring a different component to that staff. Hopkins is the workhorse by far. In this season alone he has 94 receptions.

Second year wide receiver, Christian Kirk, is the big time playmaker. Averaging over 10 yards per reception, he has found a way to score 6 times. The veteran on the staff Larry Fitzgerald has played for the Cardinals for 17 seasons. Although his stats are not flashy, the leadership and presence he brings is exactly what his young quarterback needs.

49ers vs. Cardinals Betting Odds & Lines

Bet Online has the Cardinals a 3.5 point favorite and the over/under set at 50.5.

Free Betting Pick

The 49ers have been brutal since the loss of Garoppolo. Not only are they 1-6 overall, they are 1-6 against the spread. The defense for San Francisco has been pretty bad as well since week 7 giving up 30.8 points per game.

The Cardinals are 7-7 against the spread so far this season, with a 3-4 record against the spread at home. Arizona is coming off back to back wins and have also covered the spread in both of those wins.

Besides pride, the 49ers do not really have anything to play for. Mullens suffered a late injury this past weekend, so they could potentially be on their third string starter.

Take the Cardinals -3.5 (-115) as soon as possible if Mullens is really hurt, we could see this line move quickly.

Spooky Free Pick – Arizona Cardinals -3.5

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